Late Treatment Effects and Cancer Survivor Care in the Young

Book Description This comprehensive guide describes the aftercare that is appropriate in young cancer patients and discusses in detail the risk and detection of treatment sequelae. It explains the impacts on body and mind of both the disease itself and the different risk-adapted cancer treatments currently in use. Clear guidance is provided on diagnosis and management of the principal treatment-related toxicities in different organs and organ systems and for a wide variety of tumor types. In addition, the role of genetic polymorphisms in the development of adverse therapy-related outcomes is explored, and advice offered on genetic counselling. As the number of long-term survivors of childhood cancer and of cancer in young adults continues to grow, so issues surrounding potential sequelae, second malignancies, and quality of life are becoming ever more important. All practitioners involved in the care of young cancer patients will find this book to be a helpful source of up-to-date information and assistance.

Content

Part I - Causes and Course of Severe Late Effects
1. Cardiotoxicity After Childhood Cancer Treatment
2. Kidney Disease in Childhood Cancer Survivors
3. Ototoxicity After Childhood Cancer
4. Complications in Tumour Orthopaedics
5. Causes and Course of Severe Late Effects in Young Cancer Patients: Gastrointestinal Tract
6. Pulmonary Toxicity: Causes and Course of Severe Late Effects in the Lungs of Young Cancer Patients
7. Growth Hormone Deficiency in Young Cancer Survivors
8. Endocrine Late Effects in Young Cancer Patients: Thyroid Gland
9. Disorders of Gonadal and Reproductive Function in Survivors of Childhood and Adolescent Cancer
10. Fertility Protection in Childhood, Adolescents and Young Adulthood Cancer Patients
11. Endocrine Late Effects in Young Cancer Patients: Adrenal Gland
12. Pregnancy and Birth After Cancer in the Youth
13. Obesity and Metabolic Syndrome After Childhood and Adolescent Cancer
14. Subsequent Primary Cancer After Childhood, Teenage and Young Adult Cancer
15. Neuropsychological Short Assessment of Disease- and Treatment-Related Intelligence Deficits in Children with Brain Tumors
16. Long-Term Positive and Negative Psychosocial Outcome in Young Cancer Survivors and Their Healthy Peers: Posttraumatic Stress
17. Cancer-Related Fatigue

Part II - Diagnostics in the Detection of Late Effects in Different Cancer Entities in Children, Adolescents and Young Adults
18. Late Effects After Treatment of Acute Lymphoblastic Leukemia in Childhood and Adolescence
19. Late Effects after Treatment of Acute Myeloid Leukemia in Childhood and Adolescence
20. Side Effects and Sequelae of Treatment for Chronic Myeloid Leukemia in Childhood and Adolescence
21. Late Effects After Treatment of Non-Hodgkin Lymphoma in Childhood and Adolescents
22. Late Effects After Treatment of Hodgkin Lymphoma in Childhood and Adolescence
23. Late Effects in Langerhans Cell Histiocytosis of Young Cancer Patients
24. Diagnostics and Diagnosis of Late Effects in Childhood Brain Tumour Survivors
25. Late Effects in Children and Adolescents with Neuroblastoma
26. Late Effects in Children and Adolescents with Nephroblastoma
27. Late Effects After Treatment of Hepatoblastoma and Hepatocellular Carcinoma in Childhood and Adolescents
28. Long-Term Sequelae After Retinoblastoma in Childhood and Adolescents
29. Late Effects in Children and Adolescents with Ewing Sarcoma
30. Late Effects in Children and Adolescents with Osteosarcoma
31. Late Effects in Children and Adolescents with Soft Tissue Sarcoma
32. Potential Late Effects of Rhabdoid Tumor Therapy in Childhood and Adolescents
33. Late Effects After Treatment of Malignant Endocrine Tumors in Childhood and Adolescents
34. Skin Cancer in Childhood and Adolescents: Treatment and Implications for the Long-Term Follow-Up
35. Late Effects in Young Breast Cancer Survivors
36. Long-Term Effects of Colorectal Carcinoma in Childhood and Adolescents

Part III - Final Remarks and Outlook
37. Genetic Predisposition to Late Effects: Pharmacogenomics of Cisplatin-Induced Ototoxicity
38. Physical Activity, Exercise and Sports in Young Cancer Patients
39. Developments and Risk-Adapted Strategies in Modern Pediatric Radiotherapy
40. Late Effects After Radiotherapy
41. Long-Term Follow-Up of Childhood Cancer Patients from the Point of View of a Person Affected
42. Networks of Survivorship Care for Young Cancer Patients
43. Survivors in Their Social Environment After Cure of Cancer at Young Age
44. Long-Term Follow-Up Guidelines and Organization of Long-Term Follow-Up Care for Childhood and Young Adult Cancer Survivors