- eBook:Applied Organic Chemistry: Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry
- Author:Surya K. De
- Edition:1 edition
- Data:January 26, 2021
- Pages:856 pages
The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin.
Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.
- Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry.
- Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin.
- Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area.
- User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions.
2. Condensation Reaction
3. Olefination, Metathesis, and Epoxidation Reactions
4. Miscellaneous Reactions
5. Aromatic Electrophilic Substitution Reactions
6. Pd-Catalyzed C—C Bond-Forming Reactions
7. Multicomponent Reaction
8. Oxidations and Reductions 389
9. Nomenclature and Application of Heterocyclic Compounds
10. Synthesis of Some Heterocyclic Compounds Using Named Reactions
11. Protection and Deprotection of Common Functional Groups
12. Amino Acids and Peptides
13. Functional Group Transformation
14. Synthesis of Some Drug Molecules
15. Common Laboratory Methods
16. Common Reagents in Organic Synthesis
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